The Fountain (2006)

Three stories - one each from the past, present, and future - about men in pursuit of eternity with their love. A conquistador in Mayan country searches for the tree of life to free his captive queen; a medical researcher, working with various trees, looks for a cure that will save his dying wife; a space traveler, traveling with an aged tree encapsulated within a bubble, moves toward a dying star that's wrapped in a nebula; he seeks eternity with his love. The stories intersect and parallel; the quests fail and succeed.