Harley Davidson and the Marlboro Man (1991)

The tuff biker Harley and his no less tuff Cowboy friend Marlboro learn that an old friend of them will lose his bar, because a bank wants to build a new complex there and demands 2.5 million dollars for a new contract in advance. Harley and Marlboro decide to help him by robbing the corrupt bank. Unfortunately they target the wrong safety transport and get hold of an amount of a new synthetic drug. Now they are targeted both by criminal bankers and killers of the drug mob.