Azumanga daiô (2002)

An animated series based off of the four panel managa of the same name, Azumanga Daioh is a whimsical, hilarious and very cute look at the lives of an ecclectic group of high school girls and their teachers at a Tokyo high school. As the series progresses, small bits of their lives are shown, slowly painting a bigger picture as the cast shares the ups and downs of high school life, revolving around a close-knit friendship and a lot of silliness.